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Makoto Tanaka Selected Research

F(6) ATPase

12/2018Novel anti-aging gene NM_026333 contributes to proton-induced aging via NCX1-pathway.
8/2014Coupling factor 6 attenuates CXCR4 expression through the HIF-1α and c-Src pathways and promotes endothelial apoptosis and inflammation.
11/2010Overexpression of coupling factor 6 causes cardiac dysfunction under high-salt diet in mice.
3/2009Coupling factor 6 enhances Src-mediated responsiveness to angiotensin II in resistance arterioles and cells.
3/2009Upregulation of soluble vascular endothelial growth factor receptor type 1 by endogenous prostacyclin inhibitor coupling factor 6 in vascular endothelial cells: a role of acidosis-induced c-Src activation.

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Makoto Tanaka Research Topics

Disease

20Neoplasms (Cancer)
07/2021 - 01/2002
11Bone Resorption
01/2018 - 11/2008
10Inflammation (Inflammations)
10/2022 - 03/2006
9Pain (Aches)
07/2021 - 10/2009
9Osteoporosis
07/2019 - 11/2008
8Hypertension (High Blood Pressure)
11/2018 - 10/2003
7Ulcerative Colitis
06/2022 - 09/2007
6Colitis
10/2022 - 01/2018
6Hemorrhage
11/2021 - 12/2014
6Heart Arrest (Cardiac Arrest)
01/2020 - 05/2012
6Acidosis
12/2018 - 03/2009
6Parkinson Disease (Parkinson's Disease)
12/2018 - 09/2002
4Metabolic Bone Diseases (Osteopenia)
08/2021 - 11/2008
4Heart Failure
01/2019 - 03/2006
3Taste Disorders (Taste Disorder)
10/2022 - 01/2020
3Aortic Valve Stenosis (Aortic Stenosis)
11/2021 - 08/2017
3Muscle Spasticity (Spastic)
07/2021 - 01/2015
3Inflammatory Bowel Diseases (Inflammatory Bowel Disease)
07/2020 - 07/2019
3Ischemia
01/2020 - 01/2005
3Wounds and Injuries (Trauma)
07/2019 - 01/2009
3Heart Diseases (Heart Disease)
01/2019 - 03/2013
3Lung Neoplasms (Lung Cancer)
01/2014 - 08/2010
3Neoplasm Metastasis (Metastasis)
05/2011 - 11/2003
3Alzheimer Disease (Alzheimer's Disease)
09/2005 - 06/2003
3Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease)
09/2005 - 06/2003
2Extrinsic Allergic Alveolitis (Hypersensitivity Pneumonitis)
06/2022 - 05/2021
2Coronary Artery Disease (Coronary Atherosclerosis)
11/2021 - 01/2019
2Death (Near-Death Experience)
10/2021 - 01/2020
2Spasm (Spasms)
07/2021 - 08/2017
2Cognitive Dysfunction
02/2021 - 01/2018
2Hypesthesia (Numbness)
01/2021 - 04/2009
2Aortic Valve Insufficiency (Aortic Regurgitation)
01/2021 - 01/2020
2Pneumonia (Pneumonitis)
01/2021 - 02/2008
2Crohn Disease (Crohn's Disease)
07/2020 - 05/2007
2Brain Edema (Cerebral Edema)
01/2020 - 01/2018
2Thrombosis (Thrombus)
10/2019 - 01/2019
2Liver Diseases (Liver Disease)
03/2019 - 02/2017
2Hypertrophy
01/2019 - 11/2018
2Experimental Arthritis
01/2019 - 01/2016
2Cardiovascular Diseases (Cardiovascular Disease)
01/2019 - 10/2003
2Genomic Instability
12/2018 - 01/2018
2Hypothermia
12/2018 - 01/2018
2Cardiac Arrhythmias (Arrythmia)
12/2018 - 01/2003
2Postoperative Pain
01/2018 - 08/2016
2Hyperalgesia
01/2018 - 07/2015
2Endocarditis
01/2018 - 02/2004
2Dyspnea (Shortness of Breath)
01/2018 - 04/2017
2Coronary Vasospasm (Coronary Artery Vasospasm)
08/2017 - 11/2009
2Postmenopausal Osteoporosis
06/2017 - 11/2008

Drug/Important Bio-Agent (IBA)

8Proteins (Proteins, Gene)FDA Link
08/2019 - 01/2003
8ONO-5334IBA
07/2019 - 12/2011
6AcidsIBA
07/2020 - 11/2008
6Cathepsin KIBA
01/2019 - 12/2011
5F(6) ATPaseIBA
12/2018 - 03/2009
4ZincIBA
10/2022 - 01/2020
4Analgesics (Analgesic Drugs)IBA
07/2021 - 08/2002
4deoxypyridinolineIBA
01/2016 - 11/2008
4Anesthetics (Anesthetic Agents)IBA
03/2013 - 08/2007
4Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
11/2005 - 11/2003
3SteroidsIBA
08/2021 - 11/2007
3Type C PhospholipasesIBA
08/2019 - 01/2015
3Protons (Proton)IBA
12/2018 - 01/2018
3Messenger RNA (mRNA)IBA
03/2018 - 01/2002
3Remifentanil (Ultiva)FDA Link
08/2016 - 11/2009
3OsteocalcinIBA
01/2016 - 11/2008
3Biomarkers (Surrogate Marker)IBA
01/2016 - 11/2008
3Collagen Type I (Type I Collagen)IBA
12/2015 - 11/2008
3Norepinephrine (Noradrenaline)FDA LinkGeneric
12/2015 - 06/2004
3Adenosine Triphosphate (ATP)IBA
11/2010 - 11/2005
2AntigensIBA
06/2022 - 05/2021
2CytokinesIBA
06/2022 - 08/2010
2Hydroxymethylglutaryl-CoA Reductase Inhibitors (HMG-CoA Reductase Inhibitors)IBA
11/2021 - 01/2020
2Olanzapine (Zyprexa)FDA Link
02/2021 - 07/2015
2NitrogenIBA
04/2020 - 07/2013
2Adrenal Cortex Hormones (Corticosteroids)IBA
01/2020 - 07/2015
2Therapeutic UsesIBA
07/2019 - 10/2013
2Adenosine Triphosphatases (ATPase)IBA
12/2018 - 12/2018
2SaltsIBA
12/2018 - 12/2018
2landiololIBA
12/2018 - 12/2015
2Neuroprotective AgentsIBA
12/2018 - 05/2012
2ReninIBA
11/2018 - 06/2016
2AngiotensinsIBA
11/2018 - 06/2016
2olmesartanIBA
11/2018 - 06/2016
2salicylhydroxamic acid (SHAM)IBA
01/2018 - 05/2016
2IsofluraneFDA LinkGeneric
01/2018 - 01/2002

Therapy/Procedure

13Therapeutics
10/2022 - 08/2003
10Transcatheter Aortic Valve Replacement
11/2021 - 01/2017
10General Anesthesia
01/2018 - 08/2002
7Anesthesia
02/2019 - 01/2002
6Cesarean Section (Caesarean Section)
01/2021 - 08/2007
5Cardiopulmonary Resuscitation (CPR)
01/2020 - 05/2012
3Percutaneous Coronary Intervention
11/2021 - 01/2020
3Catheters
01/2021 - 08/2016
3Segmental Mastectomy (Lumpectomy)
05/2018 - 05/2011
2Critical Care (Surgical Intensive Care)
10/2021 - 01/2020
2Analgesia
07/2021 - 03/2011
2Epidural Anesthesia
01/2021 - 04/2009
2Prostheses and Implants (Prosthesis)
01/2021 - 01/2019
2Pneumonectomy (Lung Volume Reduction)
02/2019 - 01/2015
2Induced Hypothermia
12/2018 - 01/2018